If your cough just isn't perfectly-controlled on dihydrocodeine otherwise you have any surprising Negative effects, see your health practitioner.
Our information exhibit that inside the dose range analyzed (60–one hundred twenty mg 2 times daily) the pharmacokinetics of DHC and its Lively metabolite DHM are linear in extensive metabolizers of CYP2D6; there was a linear, dose dependent improve of AUC, C
In the event you have nausea, it may well support to take this drug with foods. Ask your doctor or pharmacist about other solutions to reduce nausea (which include lying down for 1 to two hours with as minor head movement as is possible).
Acetaminophen, caffeine, and dihydrocodeine may possibly lead to severe Negative effects. Connect with your health practitioner without delay for those who have:
Use: For that management of average to moderately severe pain that is severe ample to require an opioid analgesic and for which choice treatments are inadequate.
Never take this medicine following the expiry date which is mentioned about the carton following EXP The expiry date refers back to the final working day of that month.
Dihydrocodeine is available in Japan as tablets which comprise two.five mg of dihydrocodeine phosphate and caffeine, the decongestant d,l-methylephedrine HCl, and the antihistamine chlorpheniramine, and packets of granules which effervesce like Alka-Seltzer with 10 mg of dihydrocodeine with lysozyme and chlorpheniramine, marketed for OTC sale as New Bron Answer-ACE.
Dihydrocodeine is Usually prescribed for brief periods of pain. For those who take it over a longer period of time, your body can become used to it and it'll not work at the same time. This is called tolerance.
biliary spasm (producing pain in the ideal aspect of your abdomen, especially just after taking in a food, which may possibly distribute in direction of your correct shoulder)
Confusion, emotion dizzy and vertigo (a feeling of spinning) If dihydrocodeine makes you really feel dizzy when you stand up, attempt obtaining up extremely bit by bit or remain sitting down down until you feel better. If you start to sense dizzy, lie down so that you don't faint or fall, then sit right until you're feeling better.
These Negative effects could possibly be additional possible when you first start taking dihydrocodeine but could happen at any time, for example, when starting another medicine or if a health care provider improves your dose.
Accredited indication for dihydrocodeine is the management of reasonable to moderately severe pain together with coughing and shortness of breath. As is the case with other drugs in this team, the antitussive dose tends to be a lot less than the analgesic dose, and dihydrocodeine can be a powerful cough suppressant like all other members on the instant codeine relatives (see beneath) as well as their cousins hydrocodone, oxycodone and ethylmorphine, whole opium preparations, plus the strong opioid hydromorphone.[eight][9]
Naloxone must be administered cautiously to people who are known, or suspected, being physically depending on dihydrocodeine. In these kinds of circumstances, an abrupt or complete reversal of opioid outcomes could precipitate pain and an acute withdrawal syndrome.
Dihydrocodeine decreases coughing by managing the cough reflex. Dihydrocodeine works straight on a location from the Mind that controls coughing website —it truly is sometimes called ‘the cough centre' of your brain.